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Ephedrine Chemical Structure_edited.jpg

Ephedrine

  1. The chemical structure of ephedrine includes 1 hydroxy group, 1 alcohol group and 1 amine group.

  2. Used to increase blood pressure and act as a bronchodilator.

  3. Ephedrine may be quantified in blood, plasma, or urine to monitor possible abuse by athletes, confirm a diagnosis or poisoning, or assist in a medico-legal death investigation.

  4. Ephedrine is a potent sympathomimetic that stimulates both alpha and beta receptors. The presence of an N-methyl group decreases binding affinities at alpha receptors. The hydroxy group is important for receptor binding and functional activity.

  5. Side effects are nervousness, insomnia, vertigo, headache, tachycardia, palpitation and sweating. Some patients have nausea, vomiting and anorexia.

  6. Ephedrine is a traditional Chinese medicine that has been documented in China since the Han dynasty as an anti-asthmatic and stimulant. The chemical synthesis of ephedrine was first discovered by Nagai Nagayoshi in 1885. The industrial manufacture of ephedrine in China began in the 1920s. It then spread to the West between 1926 and 1928. Ephedrine is still used today.

  7. Ephedrine is derived from a traditionally Chinese pure herb or tea called "ma huang."

  8. It is FDA approved.

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References:

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https://en.wikipedia.org/wiki/Ephedrine#Recreational_use

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https://www.rxlist.com/ephedrine-drug.htm#indications

Ephedrine: Research
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